Bottom Line: It is 100% safe to clear Ableton/Cache. Ableton Live decodes compressed audio files into temporary uncompressed sample cache files.
What is Ableton Live Cache?
Located at ~/Library/Caches/Ableton on Mac (or %LocalAppData%\Ableton\Cache on Windows), Ableton Live caches decoded audio buffers for fast project playback.
How to Delete Ableton Cache
In Ableton Live: Go to Preferences > File/Folder > Cache > Minimum Free Space. Click Purge.
Or manually via Terminal / Command Prompt:
rm -rf ~/Library/Caches/Ableton/*
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